Replicatively senescent cells are arrested in G1 and G2 phases - Figure F1
Por um escritor misterioso
Last updated 20 outubro 2024
Senescent human fibroblast cultures contain a large fraction of putative G2-arrested cells with 4N DNA content. (A) Propidium iodide (PI) staining and flow cyctometric analysis of HCA2 normal human foreskin fibroblasts. Cells entered senescence at PD73. (B) PI staining of replicatively senescent human lung fibroblasts WI-38, and IMR-90 at PDs 73 and 68 respectively. (C) The fraction of 4N cells in senescent cell population does not diminish with time. Replicatively senescent HCA2 cells were analyzed by PI staining at weekly intervals for 10 weeks stating from the onset of senescence.
Full article: Senescence from G2 arrest, revisited
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Cell cycle analysis of senescent astrocytes. (A) Representative
G2/M cell cycle arrest and senescence-like changes induced by PPKO
Full article: Senescence from G2 arrest, revisited
G1 and G2: What Happens in the Growth Phases of The Cell Cycle?
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