Viruses, Free Full-Text
Por um escritor misterioso
Last updated 20 setembro 2024
Human norovirus is a leading cause of acute gastroenteritis, driven by antigenic variants within the GII.4 genotype. Antibody responses to GII.4 vaccination in adults are shaped by immune memory. How children without extensive immune memory will respond to GII.4 vaccination has not been reported. Here, we characterized the GII.4 neutralizing antibody (nAb) landscape following natural infection using a surrogate assay and antigenic site chimera virus-like particles. We demonstrate that the nAb landscape changes with age and virus exposure. Among sites A, C, and G, nAbs from first infections are focused on sites A and C. As immunity develops with age/exposure, site A is supplemented with antibodies that bridge site A to sites C and G. Cross-site nAbs continue to develop into adulthood, accompanied by an increase in nAb to site G. Continued exposure to GII.4 2012 Sydney correlated with a shift to co-dominance of sites A and G. Furthermore, site G nAbs correlated with the broadening of nAb titer across antigenically divergent variants. These data describe fundamental steps in the development of immunity to GII.4 over a lifetime, and illustrate how the antigenicity of one pandemic variant could influence the pandemic potential of another variant through the redirection of immunodominant epitopes.
Download Free Antivirus Software
Malwarebytes Free: Free Antivirus 2024
Viruses, Free Full-Text
The ABCs of Malware A Small-Business Owner's Guide to
An RNA-dependent DNA polymerase, different from the known viral
Viruses take center stage in cellular evolution
Free Entry Virus - Colaboratory
66,493 Virus Structure Images, Stock Photos, 3D objects, & Vectors
Molecular characterization of a new virus species identified in
Ebola
Virus - Wikipedia
Capsid integrity detection of pathogenic viruses in waters: Recent
Recomendado para você
-
Pokemon Types Chart - Pokemon Black and White Guide - IGN20 setembro 2024
-
A Pokemon type chart that is much easier to read : r/gaming20 setembro 2024
-
Why was the Ice-type removed from Generation IV of Pokémon games? - Quora20 setembro 2024
-
NRFI Picks, Best Predictions and Odds 4/26/23 - Best No Run First Inning Bets20 setembro 2024
-
Evolution chart Pokemon Gen 3 (Psychic-Ice-Steel) #part520 setembro 2024
-
Building an Optimal Pokémon Team with a Quantum Computer20 setembro 2024
-
Math Clip Art--Counting Examples--100s Chart--Counting by 3s--Fill20 setembro 2024
-
2022 Team Defense Strategy Guide20 setembro 2024
-
Pokemon Type Chart with all type combinations up to this20 setembro 2024
-
Simple Pokemon Type Chart v1.1 : r/PokemonLetsGo20 setembro 2024
você pode gostar
-
Nuno Gomes operado com sucesso na Alemanha - Desporto - Correio da20 setembro 2024
-
Team Esbjerg vs WHC Buducnost BEMAX, Round 1320 setembro 2024
-
Chessregister.com20 setembro 2024
-
Anime Chat: Ai Waifu Chatbot Ver. 1.3.1 MOD Menu APK20 setembro 2024
-
Jogos de tiro tático offline – Applications sur Google Play20 setembro 2024
-
Pushing Buttons: The Super Mario Bros Movie is just fine – but what else did you expect?, Super Mario20 setembro 2024
-
games to play when your bored on google|TikTok Search20 setembro 2024
-
CLASSROOM OF THE ELITE 2 TEMPORADA EP 3 LEGENDADO PT-BR - DATA E HORA, ONDE ASSISTIR20 setembro 2024
-
s Lord Of The Rings Teaser Shows First Look At Sauron's Master20 setembro 2024
-
Como usar o Meetup para praticar inglês20 setembro 2024